Vinod Kumar and Kamalneet Kaur Pages 115 - 130 ( 16 )
Triazoles and oxadiazoles are nitrogen and nitrogen-oxygen containing heterocycles, respectively that belong to the azoles family. They have gained much attention of the synthetic and medicinal chemists as some of the natural products containing azole moiety contribute towards the development of some effective chemotherapeutic candidates. Therefore, this review mainly focuses on the existence of triazole and oxadiazole derivatives in natural sources, their isolation and biological importance besides highlighting the synthetic pathways to achieve these compounds. It covers the literature upto 2014 and would certainly provide a great insight to scientific community to bring further developments in the isolation and synthetic methodologies for triazole and oxadiazole based novel bioactive agents.
Biological activities, isolation, natural products, oxadiazole, synthesis, triazole.
Department of Chemistry, Maharishi Markandeshwar University, Mullana-Ambala-133207, India.