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Chemical Characterization and Antioxidant Potential of Athroisma proteiformis Essential Oil

[ Vol. 7 , Issue. 3 ]


Claudine Aimée Rasolohery, Boniface Erménegilde Ralaibia, Alicia Ayerdi Gotor, Franck Merlier, Rakotonirina Benja, Marcelle Rakotovao and Larbi Rhazi*   Pages 208 - 215 ( 8 )


Objective: In the present study, the essential oil of Athroisma proteiformis was characterized for the first time.

Method: GC-HRMS (Gas Chromatography-High Resolution Mass Spectrometry) was performed for qualitative and quantitative analysis of the phytochemicals present in the extract. Chemical analyses were conducted to evaluate the total phenols, total flavonoids and antioxidant activity of the extract.

Results: Of the 130 peaks detected, 50 were studied and 30 compounds were clearly identified. The main components of the extract were p-cymen-8-ol, the major compound (13.37%), followed by caryophyllene oxide (12.02%), o-cymene (7.79%), humulene epoxide II (7.62%) and limonene (7.35%). The essential oil of Athroisma proteiformis exhibited a good antioxidant activity. The Athroisma extract IC50 values were lower than those of the antioxidant standards used in the FRAP and ABTS tests, ascorbic acid and BHT, and lower than glutathione in the OH radical reducing power test. On the contrary, in the DPPH test, IC50 was higher for A. proteiformis than for ascorbic acid or BHT.

Conclusion: It can be concluded that the A. proteiformis plant can be used as a source of natural antioxidants but the consequences on human health should first be carefully studied due to the large number of compounds present in the oil.


Antioxidant activity, Asteraceae, Athroisma proteiformis, caryophyllene oxide, essential oil, p-Cymen-8-ol.


Laboratoire Plante-Santé/Laboratoire de Chimie et de Valorisation des Produits Naturels (LPS/LCVPN) Fanambinantsoa BP: 1264, Faculté des Sciences, Université Fianarantsoa, 301 Fianarantsoa, Lot IIP 109 Tambohobe BP 1264, Faculté des Sciences, Université Fianarantsoa, 301 Fianarantsoa, Institut Polytechnique LaSalle Beauvais BP 30313, Beauvais CEDEX, GEC/FRE 3580 CNRS, Université Technologique de Compiègne, 60203 Compiegne CEDEX, Institut Malgache de Recherches appliquées, Fondation Suzanne et Albert Rajoto-Ratsimamanga, Avarabohitra, Itaosy, Antananarivo, Laboratoire de Chimie et de Valorisation des Produits Naturels (LCVPN), Faculté des Sciences BP 906, Université d'Antananarivo, 101 Antananarivo, UniLaSalle BP 30313, Beauvais CEDEX

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