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The Genus Glycosmis [Rutaceae]: A Comprehensive Review on its Phytochemical and Pharmacological Perspectives

Author(s):

Mohammad Yasir, Manish Kumar Tripathi, Pushpendra Singh and Rahul Shrivastava*   Pages 1 - 27 ( 27 )

Abstract:


Medicinal plants are a rich source of a large variety of lead compounds. The plants of the genus Glycosmis or its different parts are valued for their therapeutic and medicinal qualities. Glycosmis belongs to the family Rutaceae. The genus Glycosmis is a rich source of pharmacologically and biologically active secondary metabolites, such as alkaloids, flavonoids, phenolic glycosides, quinones, terpenoids and glycerides isolated from different parts of the Glycosmis plant. About 233 phytoconstituents are isolated from this genus. All the available information on various species belonging to the genus Glycosmis was collected by electronic search [using Google books, Pubmed, SciFinder, Scirus, Google Scholar, and Web of Science] and articles of peer-reviewed journals. Recent interest in this genus has focused on isolating and identifying different phytoconstituents that exhibit potent antioxidant, antibacterial, antiviral and anticancer activities. They show good cytotoxic activity against various cancer cell lines and have also reported for good antiviral and immunomodulatory activity. To support this, convincing evidence on experimental animal models are available. This review summarizes information about the isolated compounds and their bioactivities related to the same compounds present in other plants including pharmacological activities of plant extract of Glycosmis genus.

Keywords:

Glycosmis genus, cytotoxicity, phytochemistry, pharmacology, medicinal plants.

Affiliation:

Maulana Azad National Institute of Technology - Department of Biological Science and Engineering BHOPAL, MP, Maulana Azad National Institute of Technology - Department of Biological Science and Engineering BHOPAL, MP, Maulana Azad National Institute of Technology - Department of Biological Science and Engineering BHOPAL, MP, Maulana Azad National Institute of Technology - Department of Biological Science and Engineering BHOPAL, MP



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