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Verbascum sinaiticum: A rich source of antioxidant phenylethanoid glycosides

Author(s):

Humaira Yasmeen Gondal*, Roshan Zamir, Muhammad Nisar and Muhammad Iqbal Choudhary  

Abstract:


Antioxidant potential of various solvent extracts and isolated constituents of the aerial part of Verbascum sinaiticum has been studied. Radical scavenging ability was evaluated by DPPH, ABTS and FRAP assays. Most active water-soluble part of the ethylacetate fraction afforded six phenylethanoid glycosides (1-6). Which were characterized as Verbascoside, Eukovoside, Martynoside, Jionoside D, Campenoside I and Campenoside II, on the basis of comprehensive spectral analysis. Largely, all these constituents exhibited significant antioxidant activity whereas their synergistic effect was found prominent in different solvent fractions. This is the first report on the antioxidant activity and the isolation of all these phenylethanoid glycosides from the Verbascum sinaiticum.

Keywords:

Antioxidant, Verbascum sinaiticum, phenolic glycosides, phenylethanoid glycosides, radical scavenging abilitAntioxidant, radical scavenging ability

Affiliation:

Department of Chemistry University of Sargodha, Sargodha-40100, Department of Chemistry University of Sargodha, Sargodha-40100, Department of Chemistry University of Sargodha, Sargodha-40100, H.E.J. Research Institute of Chemistry, ICCBS, University of Karachi, Karachi- 75270



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