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Antioxidant and Enzyme Inhibitory Properties of Mangiferaindica leaf Extract

Author(s):

Sainiara Begum, Archana Banerjee and Bratati De*   Pages 1 - 11 ( 11 )

Abstract:


The foliar residues of Mangifera indica tree are usually burned or used for soil amelioration except nominal uses as fodder. To add value to this agricultural waste, extracts of the leafy residues of M. indica were studied to analyze their potential as antioxidants and to inhibit the enzymes related to the management of diabetes, Alzheimer’s Disease (AD), hepatic disorders as well as to identify important phytochemicals present in the extracts. Results depicts that the leaves have notable bioactivities. The methanol extract (ME) showed much potential than ethyl acetate fraction after hydrolysis (HME) against α-amylase and α-glucosidase. The activity against the enzyme β-glucuronidase was also higher than that of the commercial β- glucuronidase inhibitor. The extract after hydrolysis showed better antioxidant and acetylcholinesterase inhibitory activities. Detection of important phytochemicals such as chrysin and myricetn, alizarin, arbutin, hydroquinone, tyrosol, taxifolin, kaempferol, mangiferin, and the vitamin alpha tocophereol, in addition to a number of organic acids, amino acids, fatty acids, sugars and polyols by GC-MS and HPTLC based analysis of the extract of M. indica leaf, also suggest the use of the leaves as sources of these important phytochemicals. More concisely HME with more number of detected metabolites found better to be used against oxidative stress as well as enzymes related to neural and liver disorders than that of ME.

Keywords:

Mango leaf, phytochemicals, bioactivity, antioxidants, enzymes

Affiliation:

Department of Botany, Surendranath College, Kolkata 700009, Department of Botany, Surendranath College, Kolkata 700009, Phytochemistry and Pharmacognosy Research Laboratory, Department of Botany, University of Calcutta, 35 Ballygunge Circular Road, Kolkata 700019



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